Expert knowledge on the compatibility and stability of injectable drugs.

Evidence-based practical guidance on the stability, compatibilities, and incompatibilities of injectable drugs commercially available worldwide, ASHP Injectable Drug Information supports health professionals in primary and secondary care settings when prescribing, preparing, and administering injectable drugs.

From early 2023, a subscription will include enhanced access to published data from ASHP Injectable Drug Information, through Drug Compatibility Checker. This unique tool provides essential knowledge on syringe, Y-Site, additive and solution compatibility.

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Speed and accuracy: Supports rapid and accurate assessment of the compatibility of various solutions and additives with a given injectable drug to maximise patient safety and enhance medication effectiveness.

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Breadth of content: Fully referenced information and tabulated results from primary research on injectable drugs commercially available in the United States and other countries

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Key information: Storage requirements and general stability information, including pH, freezing, exposure to light, sorption and filtration characteristics, and repackaging information

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Clinically relevant: Detailed compatibility tables for each drug covering solution, additive, syringe, and Y-Site

Publication Updates

08 Nov
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ASHP Injectable Drug Information November 2022 Update

This update contains 1 new monograph, 22 revised monographs, and 1 new MedWatch alert.

New monograph: Tenecteplase

Revised monographs: Conivaptan; Hydrochloride; Dexamethasone Sodium; Phosphate; Dobutamine Hydrochloride; Dopamine Hydrochloride; Etesevimab; Glycopyrrolate; Hydroxyzine Hydrochloride; Lidocaine Hydrochloride; Lorazepam; Magnesium Sulfate; Meropenem; Midazolam Hydrochloride; Milrinone Lactate; Nitroglycerin; Ondansetron Hydrochloride; Paclitaxel; Phytonadione; Sargramostim; Thiamine Hydrochloride; Trimethobenzamide Hydrochloride

New MedWatch alert: Acyclovir Sodium

Other: ASHP Injectable Drug Information – Users Guide

13 Sep
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ASHP Injectable Drug Information September 2022 Update

This update contains 5 new monographs, 92 revised monographs and 1 file.

New monographs: Bebtelovimab; Cilgavimab; Chloroprocaine Hydrochloride; Sildenafil Citrate; Tixagevimab

Revised monographs: Acyclovir Sodium; Alprostadil; Alteplase; Amiodarone Hydrochloride; Ampicillin Sodium; Ampicillin Sodium-Sulbactam Sodium; Aprepitant; Bamlanivimab; Bumetanide; Bupivacaine Hydrochloride; Calcium Chloride; Calcium Gluconate; Cangrelor Tetrasodium; Casirivimab-Imdevimab; Caspofungin Acetate; Cefiderocol Sulfate Tosylate; Ceftazidime; Ceftriaxone Sodium; Cilgavimab; Cisatracurium Besylate; Chlorpromazine Hydrochloride; Clonidine Hydrochloride; Cyclizine Lactate; Cytarabine; Dacarbazine; Daptomycin; Daunorubicin Hydrochloride; Dexamethasone Sodium Phosphate; Dexmedetomidine Hydrochloride; Diamorphine Hydrochloride; Diazepam; Diltiazem Hydrochloride; Diphenhydramine Hydrochloride; Dobutamine Hydrochloride; Dopamine Hydrochloride; Droperidol; Enoxaparin Sodium; Epinephrine Hydrochloride; Epirubicin Hydrochloride; Etesevimab; Etoposide Phosphate; Famotidine; Fat Emulsion, Intravenous; Fentanyl Citrate; Fluconazole; Fluorouracil; Gentamicin Sulfate; Haloperidol Lactate; Heparin Sodium; Hydromorphone Hydrochloride; Idarubicin Hydrochloride; Iohexol; Irinotecan Hydrochloride; Ketamine Hydrochloride; Lacosamide; Levetiracetam; Levocarnitine; Levofloxacin; Lidocaine Hydrochloride; Lorazepam; Mannitol; Mesna; Methadone Hydrochloride; Methotrexate Sodium; Metoclopramide Hydrochloride; Metronidazole; Milrinone Lactate; Morphine Sulfate; Nitroglycerin; Norepinephrine Bitartrate; Ondansetron Hydrochloride; Potassium Acetate; Propofol; Protamine Sulfate; Ranitidine Hydrochloride; Remdesivir; Rocuronium Bromide; Ropivacaine Hydrochloride; Sodium Acetate; Sodium Bicarbonate; Sodium Nitroprusside; Sotrovimab; Sufentanil Citrate; Tetracaine Hydrochloride; Theophylline; Tixagevimab; Tobramycin Sulfate; Vancomycin Hydrochloride; Vasopressin; Verapamil Hydrochloride; Vincristine Sulfate; Ziconotide Acetate.

Other file: ASHP Injectable Drug Information – Users Guide.

11 Jan
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ASHP Injectable Drug Information January 2022 Update

This update contains 4 new monographs, 133 revised monographs and 1 discontinued monograph.

New monographs: Remimazolam Besylate; Ephedrine hydrochloride; Decitabine; Sotrovimab

Revised monographs: Topotecan Hydrochloride; Tramadol Hydrochloride; Linezolid; Rocuronium Bromide; Alprostadil; Argatroban; Azithromycin; Dexmedetomidine Hydrochloride; Methylprednisolone Acetate; Mycophenolate Mofetil Hydrochloride; Ertapenem Sodium; Palonosetron Hydrochloride; Pantoprazole Sodium; Anidulafungin; Caspofungin Acetate; Levothyroxine sodium; Micafungin Sodium; Tigecycline; Voriconazole; Doripenem; Esomeprazole Sodium; Moxifloxacin Hydrochloride; Ceftaroline Fosamil; Levetiracetam; Acetaminophen; Tranexamic Acid; Dalbavancin Hydrochloride; Posaconazole; Tedizolid Phosphate; Oritavancin Diphosphate; Ceftolozane Sulfate-Tazobactam Sodium; Peramivir; Ceftazidime-Avibactam Sodium; Sodium Thiosulfate; Bacitracin; Delafloxacin Meglumine; Meropenem-Vaborbactam; Omadacycline Tosylate; Aprepitant; Cefiderocol Sulfate Tosylate; Ibuprofen; Iron Sucrose; Bamlanivimab; Casirivimab-Imdevimab; Etesevimab; Albumin Human; Amikacin Sulfate; Aminophylline; Amphotericin B; Ascorbic Acid; Atropine Sulfate; Calcium Gluconate; Cefazolin Sodium; Clindamycin Phosphate; Colistimethate Sodium; Dexamethasone Sodium Phosphate; Diazepam; Digoxin; Diphenhydramine Hydrochloride; Dobutamine Hydrochloride; Dopamine Hydrochloride; Doxycycline Hyclate; Epinephrine Hydrochloride; Fentanyl Citrate; Furosemide; Gentamicin Sulfate; Haloperidol Lactate; Heparin Sodium; Hydrocortisone Sodium Succinate; Hydromorphone Hydrochloride; Insulin; Iron Dextran; Isoproterenol Hydrochloride; Ketamine Hydrochloride; Lidocaine Hydrochloride; Magnesium Sulfate; Mannitol; Methylprednisolone Sodium Succinate; Metoclopramide Hydrochloride; Metronidazole; Morphine Sulfate; Multivitamins; Naloxone Hydrochloride; Nitroglycerin; Norepinephrine Bitartrate; Pentobarbital Sodium; Phenobarbital Sodium; Phenylephrine Hydrochloride; Phenytoin Sodium; Polymyxin B Sulfate; Potassium Chloride; Potassium Phosphates; Sodium Chloride; Sodium Nitroprusside; Sodium Phosphates; Succinylcholine Chloride; Terbutaline Sulfate; Tobramycin Sulfate; Trimethoprim-Sulfamethoxazole; Vancomycin Hydrochloride; Lorazepam; Acyclovir Sodium; Bumetanide; Labetalol Hydrochloride; Aztreonam; Imipenem-Cilastatin Sodium; Ranitidine Hydrochloride; Vasopressin; Esmolol Hydrochloride; Midazolam Hydrochloride; Famotidine; Ganciclovir Sodium; Alteplase; Octreotide Acetate; Ondansetron Hydrochloride; Vecuronium Bromide; Ciprofloxacin; Fluconazole; Amiodarone Hydrochloride; Amoxicillin Sodium-Clavulanate Potassium; Milrinone Lactate; Diltiazem Hydrochloride; Filgrastim; Ketorolac Tromethamine; Piperacillin Sodium-Tazobactam Sodium; Tacrolimus; Propofol; Cefepime Hydrochloride; Levofloxacin; Meropenem; Nicardipine Hydrochloride; Cisatracurium Besylate; Remifentanil Hydrochloride; Users Guide

Discontinued monograph: Imdevimab

13 Jul
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ASHP Injectable Drug Information July 2021 Update

This update contains 2 new monographs and 103 revised monographs.

New monographs: Oliceridine Fumarate; Etesevimab

Revised monographs: Tropisetron Hydrochloride; Linezolid; Rocuronium Bromide; Azithromycin; Caffeine Citrate; Dexmedetomidine Hydrochloride; Eptifibatide; Daptomycin; Pantoprazole Sodium; Anidulafungin; Caspofungin Acetate; Micafungin Sodium; Tigecycline; Voriconazole; Esomeprazole Sodium; Moxifloxacin Hydrochloride; Telavancin Hydrochloride; Tranexamic Acid; Posaconazole; Tedizolid Phosphate; Ceftolozane Sulfate-Tazobactam Sodium; Fosaprepitant Dimeglumine; Isavuconazonium Sulfate; Infliximab; Plazomicin Sulfate; Imipenem-Cilastatin Sodium-Relebactam; Bamlanivimab; Casirivimab; Imdevimab; Albumin Human; Amikacin Sulfate; Amphotericin B; Calcium Chloride; Calcium Gluconate; Cefazolin Sodium; Chloramphenicol Sodium Succinate; Clindamycin Phosphate; Colistimethate Sodium; Dexamethasone Sodium Phosphate; Digoxin; Diphenhydramine Hydrochloride; Dobutamine Hydrochloride; Dopamine Hydrochloride; Doxycycline Hyclate; Epinephrine Hydrochloride; Fentanyl Citrate; Gentamicin Sulfate; Haloperidol Lactate; Heparin Sodium; Hyaluronidase; Hydrocortisone Sodium Succinate; Insulin; Ketamine Hydrochloride; Lidocaine Hydrochloride; Magnesium Sulfate; Methylprednisolone Sodium Succinate; Metoclopramide Hydrochloride; Metronidazole; Morphine Sulfate; Naloxone Hydrochloride; Nitroglycerin; Norepinephrine Bitartrate; Papaverine Hydrochloride; Phenylephrine Hydrochloride; Phenytoin Sodium; Polymyxin B Sulfate; Potassium Phosphates; Sodium Bicarbonate; Tobramycin Sulfate; Vancomycin Hydrochloride; Verapamil Hydrochloride; Acyclovir Sodium; Bumetanide; Labetalol Hydrochloride; Protamine Sulfate; Aztreonam; Ceftazidime; Ranitidine Hydrochloride; Vasopressin; Esmolol Hydrochloride; Midazolam Hydrochloride; Ampicillin Sodium-Sulbactam Sodium; Famotidine; Mesna; Enalaprilat; Ondansetron Hydrochloride; Vecuronium Bromide; Ciprofloxacin; Fluconazole; Amiodarone Hydrochloride; Milrinone Lactate; Metoprolol Tartrate; Diltiazem Hydrochloride; Iopamidol; Ketorolac Tromethamine; Piperacillin Sodium-Tazobactam Sodium; Fusidate Sodium; Granisetron Hydrochloride; Propofol; Levofloxacin; Nicardipine Hydrochloride; Cisatracurium Besylate; Fosphenytoin Sodium

09 Mar
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ASHP Injectable Drug Information March 2021 Update

This update contains 10 new monographs, 40 revised monographs and 7 new MedWatch alerts.

New monographs: Amisulpride; Bamlanivimab; Bevacizumab; Casirivimab; Ferric Derisomaltose; Ferumoxytol; Imdevimab; Iron Sucrose; Meloxicam; Remdesivir

Revised monographs: Docetaxel; Clarithromycin; Tramadol Hydrochloride; Caffeine Citrate; Sterile Water for Injection; Oxycodone Hydrochloride; Pantoprazole Sodium; Ceftolozane Sulfate-Tazobactam Sodium; Methylene Blue; Meropenem-Vaborbactam; Cefazolin Sodium; Chlorothiazide Sodium; Cyclophosphamide; Dimenhydrinate; Furosemide; Hydromorphone Hydrochloride; Iron Dextran; Ketamine Hydrochloride; Lidocaine Hydrochloride; Metronidazole; Morphine Sulfate; Potassium Phosphates; Vancomycin Hydrochloride; Lorazepam; Cefuroxime Sodium; Aztreonam; Midazolam Hydrochloride; Buprenorphine Hydrochloride; Carboplatin; Enalaprilat; Ciprofloxacin; Amoxicillin Sodium; Amoxicillin Sodium-Clavulanate Potassium; Isosorbide Dinitrate; Milrinone Lactate; Salbutamol Sulfate; Adenosine; ASHP Injectable Drug Information – Notices and Editorial; ASHP Injectable Drug Information – Preface; ASHP Injectable Drug Information – Users Guide

New MedWatch alerts on the following monographs: Rocuronium Bromide; Dexmedetomidine Hydrochloride; Daptomycin; Tranexamic Acid; Heparin Sodium; Vecuronium Bromide; Amiodarone Hydrochloride

09 Jun
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ASHP Injectable Drug Information June 2020 Update

This update contains 3 new monographs, 126 revised monographs, 3 new MedWatch alerts and 6 removed MedWatch alerts.

New monographs: Cefiderocol Sulfate Tosylate; Imipenem-Cilastatin Sodium-Relebactam; Ibuprofen

Revised monographs: Linezolid; Rocuronium Bromide; Valproate Sodium; Azithromycin; Caffeine Citrate; Cloxacillin Sodium; Dexmedetomidine Hydrochloride; Acetylcysteine; Amphotericin B Liposomal; Daptomycin; Ertapenem Sodium; Pantoprazole Sodium; Caspofungin Acetate; Levothyroxine sodium; Micafungin Sodium; Voriconazole; Doripenem; Esomeprazole Sodium; Ibuprofen Lysinate; Ceftaroline Fosamil; Acetaminophen; Tedizolid Phosphate; Ceftolozane Sulfate-Tazobactam Sodium; Ceftazidime-Avibactam Sodium; Levocarnitine; Meropenem-Vaborbactam; Eravacycline Dihydrochloride; Albumin Human; Amikacin Sulfate; Amino Acids; Ampicillin Sodium; Atropine Sulfate; Calcium Chloride; Calcium Gluconate; Cefazolin Sodium; Cefoxitin Sodium; Clindamycin Phosphate; Colistimethate Sodium; Dexamethasone Sodium Phosphate; Diazepam; Digoxin; Dimenhydrinate; Diphenhydramine Hydrochloride; Dobutamine Hydrochloride; Dopamine Hydrochloride; Epinephrine Hydrochloride; Erythromycin Lactobionate; Fat Emulsion, Intravenous; Fentanyl Citrate; Furosemide; Gentamicin Sulfate; Heparin Sodium; Hydralazine Hydrochloride; Hydrocortisone Sodium Succinate; Hydromorphone Hydrochloride; Hydroxyzine Hydrochloride; Insulin; Isoproterenol Hydrochloride; Ketamine Hydrochloride; Lidocaine Hydrochloride; Magnesium Sulfate; Mannitol; Methylprednisolone Sodium Succinate; Metoclopramide Hydrochloride; Metronidazole; Morphine Sulfate; Multivitamins; Naloxone Hydrochloride; Nitroglycerin; Norepinephrine Bitartrate; Oxytocin; Penicillin G Sodium; Phenobarbital Sodium; Phenylephrine Hydrochloride; Phenytoin Sodium; Potassium Chloride; Potassium Phosphates; Procainamide Hydrochloride; Propranolol Hydrochloride; Sodium Bicarbonate; Sodium Nitroprusside; Sodium Phosphates; Tobramycin Sulfate; Trimethoprim-Sulfamethoxazole; Vancomycin Hydrochloride; Cefotaxime Sodium; Lorazepam; Bumetanide; Cefuroxime Sodium; Cyclosporine; Labetalol Hydrochloride; Ceftriaxone Sodium; Handbook on Injectable Drugs-References; Aztreonam; Benztropine Mesylate; Ceftazidime; Imipenem-Cilastatin Sodium; Vasopressin; Esmolol Hydrochloride; Midazolam Hydrochloride; Theophylline; Hetastarch in Sodium Chloride 0.9%; Octreotide Acetate; Ondansetron Hydrochloride; Vecuronium Bromide; Ciprofloxacin; Fluconazole; Foscarnet Sodium; Amiodarone Hydrochloride; Floxacillin Sodium; Isosorbide Dinitrate; Milrinone Lactate; Metoprolol Tartrate; Diltiazem Hydrochloride; Bupivacaine Hydrochloride; Piperacillin Sodium-Tazobactam Sodium; Sufentanil Citrate; Granisetron Hydrochloride; Propofol; Appendix; Cefepime Hydrochloride; Levofloxacin; Meropenem; Nicardipine Hydrochloride; Salbutamol; Cisatracurium Besylate

New MedWatch alerts on the following monographs: Phytonadione; Ranitidine Hydrochloride; Ketorolac Tromethamine

Removed MedWatch alerts on the following monographs: Alprostadil; Cyanocobalamin; Iohexol; Methylprednisolone Acetate; Mitomycin; Pyridoxine Hydrochloride

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