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We’re excited to announce the launch of two new resources: Martindale’s ADR Checker, a quick and easy tool to support you when managing patients with adverse drug reactions, and the Palliative Care Formulary, the expert source of drug information in palliative and hospice care.

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Publication Updates

12 May
Palliative Care Formulary May 2020 Update

This update contains 1 new monograph and 44 revised monographs. Parecoxib is a new monograph for this update.

The following monographs have been fully revised: *Cannabinoids; *Ketorolac trometamol; Antibacterials in palliative care; Anti-emetics; Antipsychotics; Baclofen; Bronchodilators; Celecoxib; Cellulitis in a lymphoedematous limb; Dantrolene; Diclofenac sodium; Drugs for cough; Ibuprofen; Magnesium; Medicinal products off-label; Mouthwashes; NSAIDs; Opioid antagonists – outside the CNS; Oral candidosis; Oxygen; QCG – Cellulitis in lymphoedema; QCG – Inoperable bowel obstruction; QCG – Reversal of opioid-induced respiratory depression; Rifampicin; Skeletal muscle relaxants; Tizanidine.

The following monographs have undergone minor revision: *Alfentanil; *Methadone; Buprenorphine; Depot corticosteroid injections; Diamorphine; Fentanyl; Fentanyl (transmucosal); Hydromorphone; Morphine; Opioid antagonists – within the CNS; Oxycodone; Paracetamol; Principles of use of analgesics; QCG – Use of methadone; Rubefacients; Strong opioids; Tapentadol; Theophylline.

12 May
Pharmaceutical Excipients logo
Pharmaceutical Excipients May 2020 Update

This update contains 44 updated monographs, 1 new Chapter on excipient selection for inhaled formulations, and 1 new monograph for Silicon Dioxide, hydrated. Hydrophobic Colloidal Silica has been renamed Silicon Dioxide, Hydrophobic; and Colloidal Silicon Dioxide has been renamed Silicon Dioxide, Anhydrous. The British Pharmacopoeia, European Pharmacopoeia, and USP-NF information have been globally updated.

New Chapter: Formulation Considerations for Orally Inhaled Dosage Forms.

New Monograph: Silicon Dioxide, hydrated.

Revised monographs: Aliphatic Polyesters; Ammonium Phosphate; Ammonium Sulfate; Benzethonium Chloride; Benzoic Acid; Butylated Hydroxyanisole; Butyl Stearate; Butylated Hydroxytoluene; Calcium Chloride; Calcium Hydroxide; Calcium Silicate; Castor Oil, Hydrogenated; Cetyl Alcohol; Copovidone; Croscarmellose Sodium; Cyclomethicone; Ethylene Glycol Vinyl Alcohol Copolymer; Hexetidine; Hydroxyethyl Cellulose; Hypromellose; Hypromellose Acetate Succinate; Hypromellose Phthalate; Inulin; Isopropyl Alcohol; Linoleic Acid; Lysine Hydrochloride; Maleic Acid; Maltodextrin; Maltol; Monoethanolamine; Palm Kernel Oil; Petrolatum; Polyethylene Oxide; Polyvinyl Alcohol; Potassium Benzoate; Shellac; Sodium Ascorbate; Sodium Carbonate; Sodium Sulfite; Sorbitol; Sunflower Oil; Suppository Bases, Hard Fat; Titanium Dioxide; Zinc Oxide.

12 May
Stockley's Interactions Checker_logo
Stockley’s Interactions Checker May 2020 Update

New and updated interactions now available

For May, 330 new interactions have been added, and 322 existing interactions have been updated.

12 May
Stockleys Drug Interactions_logo
Stockley’s Drug Interactions May 2020 update

Stockley’s Drug Interactions update with new and revised monographs.

This update contains 3 new monographs and 12 revised monographs. The monographs on tetrabenazine have been fully revised and updated, and the related drugs, deutetrabenazine and valbenazine have been added.

 

12 May
British National Formulary for Children logo
BNF for Children May 2020 Update

This update contains 3 significant changes, 5 dose changes and 1 new preparation.

Significant Changes:
• Benzodiazepines: reminder of risk of potentially fatal respiratory depression [MHRA/CHM advice] (advice in alprazolam, chlordiazepoxide hydrochloride, clobazam, clonazepam, diazepam, flurazepam, loprazolam, lorazepam, lormetazepam, midazolam, nitrazepam, oxazepam, temazepam; see example in diazepam).
• COVID-19: new guidance incorporating a collection of resources.
• Opioids: reminder of risk of potentially fatal respiratory depression [MHRA/CHM advice] (advice in alfentanil, buprenorphine, codeine phosphate, diamorphine hydrochloride, dihydrocodeine tartrate, dipipanone hydrochloride, fentanyl, hydromorphone hydrochloride, meptazinol, methadone hydrochloride, morphine, oxycodone hydrochloride, pentazocine, pethidine hydrochloride, remifentanil, sufentanil, tapentadol, tramadol hydrochloride; see example in morphine).

Dose Changes:

• Betamethasone with clioquinol [updated child age range].
• Digoxin [clarification of maximum doses for children 5-9 years].
• Glucagon [update to age ranges for hypoglycaemia].
• Idursulfase [updated age range].
• Sodium fluoride [updating dosing for prophylaxis of dental caries].

New Preparations: Cytotect® [cytomegalovirus immunoglobulin].

For further details on changes in the BNFC click on https://www.medicinescomplete.com/#/content/bnfc/PHP107699?hspl=changes

12 May
AHFS Drug Information logo
AHFS May 2020 Update

This update contains 5 new monographs, 38 revised monographs, 1 discontinued monograph and 3 new MedWatch alerts.

New monographs: Isatuximab-irfc; Rimegepant; Bempedoic Acid; Eptinezumab-jjmr; Cenobamate.

Revised monographs: Sirolimus; Montelukast; Lopinavir and Ritonavir; Nitric Oxide; Pregabalin; Lacosamide; Tocilizumab; Lorcaserin; Sarilumab; Patisiran; Mogamulizumab-kpkc; Doravirine; Doravirine, Lamivudine, and Tenofovir Disoproxil; Inotersen; Moxetumomab Pasudotox-tdfk; Baloxavir; Cladribine; Indomethacin; Ibuprofen; Orphenadrine; Chloroquine; Hydroxychloroquine; Chlorzoxazone; Phytonadione; MethylPREDNISolone; Captopril; Corticosteroids General Statement; Miotics General Statement; Diflunisal; CloZAPine; Cladribine; Gabapentin; Dalteparin; Topiramate; Valsartan; Azithromycin; Zanamivir; Oseltamivir.

Discontinued monographs: Ambenonium.

New MedWatch alerts on the following monographs: Montelukast; Lorcaserin; CloZAPine.

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